node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACLY | ACO1 | ENSMFAP00000004443 | ENSMFAP00000003967 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | 0.962 |
ACLY | ACO2 | ENSMFAP00000004443 | ENSMFAP00000024254 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Aconitase 2. | 0.976 |
ACLY | ACSS1 | ENSMFAP00000004443 | ENSMFAP00000033088 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Acetyl-coenzyme A synthetase. | 0.574 |
ACLY | ACSS2 | ENSMFAP00000004443 | ENSMFAP00000036894 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Acyl-CoA synthetase short chain family member 2. | 0.556 |
ACLY | CS | ENSMFAP00000004443 | ENSMFAP00000004989 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | 0.997 |
ACLY | DLAT | ENSMFAP00000004443 | ENSMFAP00000013893 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.979 |
ACLY | MDH1 | ENSMFAP00000004443 | ENSMFAP00000030058 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Malate dehydrogenase. | 0.960 |
ACLY | MDH2 | ENSMFAP00000004443 | ENSMFAP00000011294 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Malate dehydrogenase, mitochondrial. | 0.970 |
ACLY | SDHA | ENSMFAP00000004443 | ENSMFAP00000011190 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor. Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.953 |
ACLY | SDHB | ENSMFAP00000004443 | ENSMFAP00000007981 | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.867 |
ACO1 | ACLY | ENSMFAP00000003967 | ENSMFAP00000004443 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | 0.962 |
ACO1 | ACO2 | ENSMFAP00000003967 | ENSMFAP00000024254 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Aconitase 2. | 0.919 |
ACO1 | CS | ENSMFAP00000003967 | ENSMFAP00000004989 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | 0.996 |
ACO1 | MDH1 | ENSMFAP00000003967 | ENSMFAP00000030058 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Malate dehydrogenase. | 0.441 |
ACO1 | MDH2 | ENSMFAP00000003967 | ENSMFAP00000011294 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Malate dehydrogenase, mitochondrial. | 0.597 |
ACO1 | SDHA | ENSMFAP00000003967 | ENSMFAP00000011190 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor. Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.712 |
ACO1 | SDHB | ENSMFAP00000003967 | ENSMFAP00000007981 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.676 |
ACO2 | ACLY | ENSMFAP00000024254 | ENSMFAP00000004443 | Aconitase 2. | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. | 0.976 |
ACO2 | ACO1 | ENSMFAP00000024254 | ENSMFAP00000003967 | Aconitase 2. | Aconitase 1; Belongs to the aconitase/IPM isomerase family. | 0.919 |
ACO2 | ACSS1 | ENSMFAP00000024254 | ENSMFAP00000033088 | Aconitase 2. | Acetyl-coenzyme A synthetase. | 0.421 |