PFDN4 protein (Macaca fascicularis) - STRING interaction network

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PFDN4

Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family. (134 aa)

Predicted Functional Partners:

VBP1

0.996

PFDN1

0.996

PFDN6

0.996

PFDN2

0.992

PFDN5

0.984

PDRG1

0.972

ENSMFAP00000007861

0.966

ENSMFAP00000039936

0.951

CCT2

0.829

CCT4

0.821

Your Current Organism:

Macaca fascicularis

NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCT2	CCT4	ENSMFAP00000022038	ENSMFAP00000016404	T-complex protein 1 subunit beta; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin.	T-complex protein 1 subunit delta.	0.999
CCT2	ENSMFAP00000007861	ENSMFAP00000022038	ENSMFAP00000007861	T-complex protein 1 subunit beta; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin.	Uncharacterized protein.	0.718
CCT2	ENSMFAP00000039936	ENSMFAP00000022038	ENSMFAP00000039936	T-complex protein 1 subunit beta; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin.	Uncharacterized protein.	0.652
CCT2	PFDN1	ENSMFAP00000022038	ENSMFAP00000025924	T-complex protein 1 subunit beta; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin.	Prefoldin subunit 1.	0.730
CCT2	PFDN2	ENSMFAP00000022038	ENSMFAP00000021514	T-complex protein 1 subunit beta; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin.	Prefoldin subunit 2.	0.791
CCT2	PFDN4	ENSMFAP00000022038	ENSMFAP00000005000	T-complex protein 1 subunit beta; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin.	Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family.	0.829
CCT2	PFDN5	ENSMFAP00000022038	ENSMFAP00000033260	T-complex protein 1 subunit beta; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin.	Uncharacterized protein.	0.718
CCT2	PFDN6	ENSMFAP00000022038	ENSMFAP00000040928	T-complex protein 1 subunit beta; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin.	Prefoldin subunit 6.	0.731
CCT2	VBP1	ENSMFAP00000022038	ENSMFAP00000017904	T-complex protein 1 subunit beta; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin.	Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family.	0.748
CCT4	CCT2	ENSMFAP00000016404	ENSMFAP00000022038	T-complex protein 1 subunit delta.	T-complex protein 1 subunit beta; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin.	0.999
CCT4	ENSMFAP00000007861	ENSMFAP00000016404	ENSMFAP00000007861	T-complex protein 1 subunit delta.	Uncharacterized protein.	0.789
CCT4	ENSMFAP00000039936	ENSMFAP00000016404	ENSMFAP00000039936	T-complex protein 1 subunit delta.	Uncharacterized protein.	0.758
CCT4	PFDN1	ENSMFAP00000016404	ENSMFAP00000025924	T-complex protein 1 subunit delta.	Prefoldin subunit 1.	0.748
CCT4	PFDN2	ENSMFAP00000016404	ENSMFAP00000021514	T-complex protein 1 subunit delta.	Prefoldin subunit 2.	0.863
CCT4	PFDN4	ENSMFAP00000016404	ENSMFAP00000005000	T-complex protein 1 subunit delta.	Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family.	0.821
CCT4	PFDN5	ENSMFAP00000016404	ENSMFAP00000033260	T-complex protein 1 subunit delta.	Uncharacterized protein.	0.789
CCT4	PFDN6	ENSMFAP00000016404	ENSMFAP00000040928	T-complex protein 1 subunit delta.	Prefoldin subunit 6.	0.862
CCT4	VBP1	ENSMFAP00000016404	ENSMFAP00000017904	T-complex protein 1 subunit delta.	Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family.	0.816
ENSMFAP00000007861	CCT2	ENSMFAP00000007861	ENSMFAP00000022038	Uncharacterized protein.	T-complex protein 1 subunit beta; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin.	0.718
ENSMFAP00000007861	CCT4	ENSMFAP00000007861	ENSMFAP00000016404	Uncharacterized protein.	T-complex protein 1 subunit delta.	0.789

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