Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CWC25CWC25 spliceosome associated protein homolog. (361 aa)    
Predicted Functional Partners:
DHX38
DEAH-box helicase 38.
   
 0.945
CWC22
CWC22 spliceosome associated protein homolog.
   
 0.945
CDC40
Cell division cycle 40.
    
 0.932
SYF2
SYF2 pre-mRNA splicing factor.
   
 0.896
PPWD1
Peptidylprolyl isomerase domain and WD repeat containing 1.
    
 0.881
WDR70
WD repeat domain 70.
    
  0.863
SRRM2
Serine/arginine repetitive matrix 2.
   
 0.840
DHX35
DEAH-box helicase 35.
   
 0.838
SLU7
Pre-mRNA-splicing factor SLU7; Required for pre-mRNA splicing as component of the spliceosome. Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation. Belongs to the SLU7 family.
   
 0.821
PRPF8
Pre-mRNA processing factor 8.
    
 0.806
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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