STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HEG1Heart development protein with EGF like domains 1. (1285 aa)    
Predicted Functional Partners:
KRIT1
Uncharacterized protein.
    
 
 0.942
RAP1B
Ras-related protein Rap-1b; GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function (By similarity); Belongs to the small GTPase superfamily. Ras family.
    
 0.570
MUC1
Mucin 1, cell surface associated.
   
 0.568
MUC20
Mucin 20, cell surface associated.
     
 0.562
MUC6
Mucin 6, oligomeric mucus/gel-forming.
    
 0.549
INO80D
INO80 complex subunit D.
   
 
 0.537
MUC15
Mucin 15, cell surface associated.
     
 0.490
GALNT14
Polypeptide N-acetylgalactosaminyltransferase.
    
 0.482
ASB2
Ankyrin repeat and SOCS box containing 2.
   
 0.463
CCM2
CCM2 scaffold protein.
   
  
 0.461
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.