STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TIPARPTCDD inducible poly(ADP-ribose) polymerase. (657 aa)    
Predicted Functional Partners:
KDM2B
Lysine demethylase 2B.
    
 0.651
SNRNP200
Small nuclear ribonucleoprotein U5 subunit 200.
      
 0.623
ABL1
ABL proto-oncogene 1, non-receptor tyrosine kinase.
     
 0.616
C1orf115
Chromosome 1 open reading frame 115.
      
 0.612
RASGEF1C
Ras-GEF domain-containing family member 1C; Guanine nucleotide exchange factor (GEF).
      
 0.612
TMEM244
Transmembrane protein 244.
      
 0.612
LYZL4
Lysozyme like 4; Belongs to the glycosyl hydrolase 22 family.
      
 0.609
PARP1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
    
 
 0.546
AATK
Apoptosis associated tyrosine kinase.
      
 0.530
ZFAND5
Zinc finger AN1-type containing 5.
      
 0.523
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.