STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF4Uncharacterized protein. (1864 aa)    
Predicted Functional Partners:
APC
APC regulator of WNT signaling pathway.
   
 0.993
APC2
APC regulator of WNT signaling pathway 2.
   
 0.975
RAC3
Rac family small GTPase 3.
    
 0.944
RAC2
Rac family small GTPase 2.
    
 0.944
SPATA13
Uncharacterized protein.
    
 
0.906
CDHR5
Cadherin related family member 5.
   
  
 0.593
GABRA2
Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
 
 0.582
KHDRBS2
KH RNA binding domain containing, signal transduction associated 2.
   
  
 0.574
ITSN2
Intersectin 2.
    
0.536
MAPRE3
Microtubule associated protein RP/EB family member 3.
      
 0.532
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.