Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
F13A1Coagulation factor XIII A chain. (732 aa)    
Predicted Functional Partners:
F13B
Coagulation factor XIII B chain.
    
 0.999
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
    
 0.987
FGA
Fibrinogen alpha chain.
   
 0.809
HSPB1
SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.
    
   0.770
LYVE1
Lymphatic vessel endothelial hyaluronan receptor 1.
   
 
 0.694
MRC1
Mannose receptor C-type 1.
   
 0.682
CLEC10A
C-type lectin domain containing 10A.
   
 0.680
SERPINC1
Serpin family C member 1; Belongs to the serpin family.
     
 0.598
LOXHD1
Lipoxygenase homology domains 1.
    
 
 0.595
SERPIND1
Serpin family D member 1; Belongs to the serpin family.
     
 0.591
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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