Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
STRADASTE20-related kinase adapter protein alpha; Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation (By similarity); Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. (431 aa)    
Predicted Functional Partners:
STK11
Serine/threonine kinase 11; Belongs to the protein kinase superfamily.
    
 0.996
CAB39
Calcium binding protein 39.
    
 0.996
CAB39L
Calcium binding protein 39 like.
    
 0.994
PRKAA2
Non-specific serine/threonine protein kinase.
    
0.961
STRADB
STE20 related adaptor beta.
  
  
 
0.954
PRKAA1
Non-specific serine/threonine protein kinase.
    
0.948
PRKAG3
Protein kinase AMP-activated non-catalytic subunit gamma 3.
     
 0.858
PRKAB2
Protein kinase AMP-activated non-catalytic subunit beta 2.
     
 0.854
PRKAB1
Protein kinase AMP-activated non-catalytic subunit beta 1.
     
 0.839
PRKAG1
Uncharacterized protein.
     
 0.813
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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