STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRF9IRF tryptophan pentad repeat domain-containing protein. (392 aa)    
Predicted Functional Partners:
STAT2
Signal transducer and activator of transcription.
   
 0.999
STAT1
Signal transducer and activator of transcription.
   
 0.999
ISG15
ISG15 ubiquitin like modifier.
   
 0.958
STAT3
Signal transducer and activator of transcription.
   
 0.901
STAT4
Signal transducer and activator of transcription.
   
 0.897
TYK2
Tyrosine-protein kinase.
    
 0.864
JAK1
Tyrosine-protein kinase.
    
 0.856
MX1
Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
   
 
 0.833
STAT5A
Signal transducer and activator of transcription.
   
 0.818
STAT5B
Signal transducer and activator of transcription.
   
 0.818
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.