Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IRF9IRF tryptophan pentad repeat domain-containing protein. (392 aa)    
Predicted Functional Partners:
STAT2
Signal transducer and activator of transcription.
   
 0.999
STAT1
Signal transducer and activator of transcription.
   
 0.999
TYK2
Tyrosine-protein kinase.
    
 0.989
JAK1
Tyrosine-protein kinase.
    
 0.989
STAT4
Signal transducer and activator of transcription.
   
 0.989
ISG15
ISG15 ubiquitin like modifier.
   
 0.985
STAT3
Signal transducer and activator of transcription.
   
 0.982
STAT6
Signal transducer and activator of transcription.
   
 0.970
STAT5A
Signal transducer and activator of transcription.
   
 0.968
IFNAR2
Uncharacterized protein.
    
 0.897
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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