node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACAA1 | ACAA2 | ENSMFAP00000025586 | ENSMFAP00000001918 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | 0.917 |
ACAA1 | ACADS | ENSMFAP00000025586 | ENSMFAP00000008657 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Acyl-CoA dehydrogenase short chain. | 0.984 |
ACAA1 | ACAT1 | ENSMFAP00000025586 | ENSMFAP00000027085 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-CoA acetyltransferase, mitochondrial; This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism. Belongs to the thiolase-l [...] | 0.925 |
ACAA1 | ACAT2 | ENSMFAP00000025586 | ENSMFAP00000021500 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | 0.920 |
ACAA1 | ACOX1 | ENSMFAP00000025586 | ENSMFAP00000019384 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.988 |
ACAA1 | ALDH6A1 | ENSMFAP00000025586 | ENSMFAP00000043210 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Aldehyde dehydrogenase 6 family member A1. | 0.951 |
ACAA1 | ECHDC1 | ENSMFAP00000025586 | ENSMFAP00000013827 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Ethylmalonyl-CoA decarboxylase 1; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.969 |
ACAA1 | EHHADH | ENSMFAP00000025586 | ENSMFAP00000020203 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.989 |
ACAA1 | HADHA | ENSMFAP00000025586 | ENSMFAP00000042038 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.982 |
ACAA1 | HADHB | ENSMFAP00000025586 | ENSMFAP00000016446 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Trifunctional enzyme subunit beta, mitochondrial; Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA. Among the enzymes involved in this pathway, the trifunctional enzyme exhibits specificity for long-chain fatty acids. Mitochondrial trifunctional enzyme is a heterotetrameric complex composed of two proteins, the trifunctional enz [...] | 0.924 |
ACAA2 | ACAA1 | ENSMFAP00000001918 | ENSMFAP00000025586 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | 0.917 |
ACAA2 | ACADS | ENSMFAP00000001918 | ENSMFAP00000008657 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Acyl-CoA dehydrogenase short chain. | 0.978 |
ACAA2 | ACAT1 | ENSMFAP00000001918 | ENSMFAP00000027085 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-CoA acetyltransferase, mitochondrial; This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism. Belongs to the thiolase-l [...] | 0.926 |
ACAA2 | ACAT2 | ENSMFAP00000001918 | ENSMFAP00000021500 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | 0.918 |
ACAA2 | ACOX1 | ENSMFAP00000001918 | ENSMFAP00000019384 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.978 |
ACAA2 | ALDH6A1 | ENSMFAP00000001918 | ENSMFAP00000043210 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Aldehyde dehydrogenase 6 family member A1. | 0.942 |
ACAA2 | ECHDC1 | ENSMFAP00000001918 | ENSMFAP00000013827 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Ethylmalonyl-CoA decarboxylase 1; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.959 |
ACAA2 | EHHADH | ENSMFAP00000001918 | ENSMFAP00000020203 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.988 |
ACAA2 | HADHA | ENSMFAP00000001918 | ENSMFAP00000042038 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.988 |
ACAA2 | HADHB | ENSMFAP00000001918 | ENSMFAP00000016446 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. | Trifunctional enzyme subunit beta, mitochondrial; Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA. Among the enzymes involved in this pathway, the trifunctional enzyme exhibits specificity for long-chain fatty acids. Mitochondrial trifunctional enzyme is a heterotetrameric complex composed of two proteins, the trifunctional enz [...] | 0.954 |