Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
C16orf74Chromosome 16 open reading frame 74. (76 aa)    
Predicted Functional Partners:
PPP3CA
Serine/threonine-protein phosphatase.
    
 
 0.906
EMC1
ER membrane protein complex subunit 1.
    
 
 0.842
UNC119
Unc-119 lipid binding chaperone.
    
   0.800
EMC2
ER membrane protein complex subunit 2.
   
 
 0.758
EMC3
ER membrane protein complex subunit 3; Belongs to the EMC3 family.
   
 
 0.755
EMC7
ER membrane protein complex subunit 7; Belongs to the EMC7 family.
   
 
 0.745
EMC4
ER membrane protein complex subunit 4; Belongs to the EMC4 family.
   
 
 0.734
EMC10
ER membrane protein complex subunit 10.
    
 
 0.732
EMC6
ER membrane protein complex subunit 6.
   
 
 0.695
MMGT1
Membrane magnesium transporter 1.
    
 
 0.646
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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