node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDC6 | CDT1 | ENSMFAP00000025560 | ENSMFAP00000024836 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Chromatin licensing and DNA replication factor 1. | 0.999 |
CDC6 | ICK | ENSMFAP00000025560 | ENSMFAP00000009140 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Intestinal cell kinase. | 0.765 |
CDC6 | MCM2 | ENSMFAP00000025560 | ENSMFAP00000012461 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.998 |
CDC6 | MCM3 | ENSMFAP00000025560 | ENSMFAP00000004419 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.997 |
CDC6 | MCM4 | ENSMFAP00000025560 | ENSMFAP00000021240 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.999 |
CDC6 | MCM7 | ENSMFAP00000025560 | ENSMFAP00000024899 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.998 |
CDC6 | ORC2 | ENSMFAP00000025560 | ENSMFAP00000006230 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Origin recognition complex subunit 2. | 0.993 |
CDC6 | ORC3 | ENSMFAP00000025560 | ENSMFAP00000029337 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Origin recognition complex subunit 3. | 0.998 |
CDC6 | ORC4 | ENSMFAP00000025560 | ENSMFAP00000016870 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | 0.998 |
CDC6 | ORC5 | ENSMFAP00000025560 | ENSMFAP00000005968 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Origin recognition complex subunit 5. | 0.998 |
CDT1 | CDC6 | ENSMFAP00000024836 | ENSMFAP00000025560 | Chromatin licensing and DNA replication factor 1. | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.999 |
CDT1 | ICK | ENSMFAP00000024836 | ENSMFAP00000009140 | Chromatin licensing and DNA replication factor 1. | Intestinal cell kinase. | 0.760 |
CDT1 | MCM2 | ENSMFAP00000024836 | ENSMFAP00000012461 | Chromatin licensing and DNA replication factor 1. | DNA helicase; Belongs to the MCM family. | 0.996 |
CDT1 | MCM3 | ENSMFAP00000024836 | ENSMFAP00000004419 | Chromatin licensing and DNA replication factor 1. | DNA helicase; Belongs to the MCM family. | 0.998 |
CDT1 | MCM4 | ENSMFAP00000024836 | ENSMFAP00000021240 | Chromatin licensing and DNA replication factor 1. | DNA helicase; Belongs to the MCM family. | 0.998 |
CDT1 | MCM7 | ENSMFAP00000024836 | ENSMFAP00000024899 | Chromatin licensing and DNA replication factor 1. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.998 |
CDT1 | ORC2 | ENSMFAP00000024836 | ENSMFAP00000006230 | Chromatin licensing and DNA replication factor 1. | Origin recognition complex subunit 2. | 0.996 |
CDT1 | ORC3 | ENSMFAP00000024836 | ENSMFAP00000029337 | Chromatin licensing and DNA replication factor 1. | Origin recognition complex subunit 3. | 0.998 |
CDT1 | ORC4 | ENSMFAP00000024836 | ENSMFAP00000016870 | Chromatin licensing and DNA replication factor 1. | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | 0.998 |
CDT1 | ORC5 | ENSMFAP00000024836 | ENSMFAP00000005968 | Chromatin licensing and DNA replication factor 1. | Origin recognition complex subunit 5. | 0.998 |