Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GPR61G protein-coupled receptor 61; Belongs to the G-protein coupled receptor 1 family. (451 aa)    
Predicted Functional Partners:
ADGRG3
Adhesion G protein-coupled receptor G3; Belongs to the G-protein coupled receptor 2 family.
      
 0.687
ADGRA2
Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family.
     
 0.679
GPR82
G protein-coupled receptor 82.
      
 0.656
GPRC5C
G protein-coupled receptor class C group 5 member C.
      
 0.631
GNG2
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
  0.574
GPER1
G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.542
SKOR1
SKI family transcriptional corepressor 1.
      
 0.536
FST
Follistatin.
      
 0.533
ADGRG5
Adhesion G protein-coupled receptor G5.
      
 0.531
GJB6
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
   
   0.529
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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