Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSMFAP00000010025Uncharacterized protein. (137 aa)    
Predicted Functional Partners:
CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family.
    
 0.872
CIAO3
Cytosolic iron-sulfur assembly component 3; Belongs to the NARF family.
   
 0.821
MMS19
MMS19 homolog, cytosolic iron-sulfur assembly component.
    
 0.788
NARF
Nuclear prelamin A recognition factor; Belongs to the NARF family.
   
 0.692
ERCC2
ERCC excision repair 2, TFIIH core complex helicase subunit.
    
 0.671
IREB2
Iron responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family.
    
 
 0.560
FBXL5
F-box and leucine rich repeat protein 5.
    
 
 0.549
CIAO2B
Cytosolic iron-sulfur assembly component 2B.
    
   0.517
POLD1
DNA polymerase.
    
 0.483
DNA2
Uncharacterized protein.
    
 0.422
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.