Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DACH2Dachshund family transcription factor 2. (599 aa)    
Predicted Functional Partners:
DACH1
Dachshund family transcription factor 1.
   
   0.866
EYA4
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
    
 
 0.630
EYA1
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
    
 
 0.630
EYA3
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
    
 
 0.630
EYA2
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
    
 
 0.630
POF1B
POF1B actin binding protein.
      
 0.479
C1GALT1C1
C1GALT1 specific chaperone 1.
      
 0.477
MED15
Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.448
NAGK
N-acetylglucosamine kinase.
    
   0.433
SMAD4
Mothers against decapentaplegic homolog.
    
 
 0.413
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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