Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H2BC1Histone H2B; Belongs to the histone H2B family. (127 aa)    
Predicted Functional Partners:
H2BC3
Histone H2B; Belongs to the histone H2B family.
   
  0.933
H2BC18
Histone H2B; Belongs to the histone H2B family.
   
  0.933
H2BC5
Histone H2B; Belongs to the histone H2B family.
   
  0.894
HIST2H2BE
Histone H2B; Belongs to the histone H2B family.
   
  0.894
ENSMFAP00000006991
Histone H2B; Belongs to the histone H2B family.
   
  0.865
HIST1H2BO
Histone H2B; Belongs to the histone H2B family.
   
  0.865
H2BU1
Histone H2B; Belongs to the histone H2B family.
   
  0.863
H2AC6
Histone H2A; Belongs to the histone H2A family.
  
 0.839
H2AC20
Histone H2A; Belongs to the histone H2A family.
  
 0.829
HDAC2
Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 0.822
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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