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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
REG4Regenerating family member 4. (158 aa)    
Predicted Functional Partners:
SPINK8
Serine peptidase inhibitor, Kazal type 8 (putative).
      
 0.724
ENC1
Ectodermal-neural cortex 1.
      
 0.554
PNOC
Prepronociceptin.
      
 0.529
TFF2
Trefoil factor 2.
   
  
 0.493
SPINK4
Serine peptidase inhibitor, Kazal type 4.
   
  
 0.470
TMPRSS2
Transmembrane serine protease 2; Belongs to the peptidase S1 family.
    
 0.441
CDX1
Caudal type homeobox 1.
   
  
 0.405
DMPK
DM1 protein kinase.
    
 0.405
PHGDH
D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
      
 0.404
NARS2
Asparaginyl-tRNA synthetase 2, mitochondrial.
      
 0.404
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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