GPR135 protein (Macaca fascicularis) - STRING interaction network

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GPR135

G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family. (499 aa)

Predicted Functional Partners:

NPFF

0.799

ARRB2

0.673

ARRB1

0.612

RCVRN

0.593

ADGRB2

0.586

GRK7

0.584

ARR3

0.578

SAG

0.578

RLN3

0.564

GNAI1

0.539

Your Current Organism:

Macaca fascicularis

NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADGRB2	GPR135	ENSMFAP00000015590	ENSMFAP00000010071	Adhesion G protein-coupled receptor B2; Belongs to the G-protein coupled receptor 2 family.	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	0.586
ARR3	GPR135	ENSMFAP00000008914	ENSMFAP00000010071	Arrestin 3.	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	0.578
ARR3	GRK7	ENSMFAP00000008914	ENSMFAP00000003950	Arrestin 3.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.492
ARR3	RCVRN	ENSMFAP00000008914	ENSMFAP00000011241	Arrestin 3.	Recoverin.	0.617
ARRB1	ARRB2	ENSMFAP00000031367	ENSMFAP00000008309	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	Arrestin beta 2.	0.994
ARRB1	GNAI1	ENSMFAP00000031367	ENSMFAP00000008751	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	G protein subunit alpha i1.	0.438
ARRB1	GPR135	ENSMFAP00000031367	ENSMFAP00000010071	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	0.612
ARRB1	GRK7	ENSMFAP00000031367	ENSMFAP00000003950	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.905
ARRB1	RCVRN	ENSMFAP00000031367	ENSMFAP00000011241	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	Recoverin.	0.414
ARRB2	ARRB1	ENSMFAP00000008309	ENSMFAP00000031367	Arrestin beta 2.	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	0.994
ARRB2	GPR135	ENSMFAP00000008309	ENSMFAP00000010071	Arrestin beta 2.	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	0.673
ARRB2	GRK7	ENSMFAP00000008309	ENSMFAP00000003950	Arrestin beta 2.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.894
ARRB2	RCVRN	ENSMFAP00000008309	ENSMFAP00000011241	Arrestin beta 2.	Recoverin.	0.414
GNAI1	ARRB1	ENSMFAP00000008751	ENSMFAP00000031367	G protein subunit alpha i1.	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	0.438
GNAI1	GPR135	ENSMFAP00000008751	ENSMFAP00000010071	G protein subunit alpha i1.	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	0.539
GPR135	ADGRB2	ENSMFAP00000010071	ENSMFAP00000015590	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	Adhesion G protein-coupled receptor B2; Belongs to the G-protein coupled receptor 2 family.	0.586
GPR135	ARR3	ENSMFAP00000010071	ENSMFAP00000008914	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	Arrestin 3.	0.578
GPR135	ARRB1	ENSMFAP00000010071	ENSMFAP00000031367	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	0.612
GPR135	ARRB2	ENSMFAP00000010071	ENSMFAP00000008309	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	Arrestin beta 2.	0.673
GPR135	GNAI1	ENSMFAP00000010071	ENSMFAP00000008751	G protein-coupled receptor 135; Belongs to the G-protein coupled receptor 1 family.	G protein subunit alpha i1.	0.539

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