Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DPYSL2Dihydropyrimidinase like 2. (712 aa)    
Predicted Functional Partners:
DPYSL5
Dihydropyrimidinase like 5.
  
 
0.993
DPYSL3
Dihydropyrimidinase like 3.
   
  0.986
GSK3B
Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.
   
 0.979
CDK5
Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.
    
 0.975
CRMP1
Collapsin response mediator protein 1.
   
  0.969
FES
Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
    
 0.938
DPYSL4
Dihydropyrimidinase like 4.
   
  0.874
NUMB
NUMB endocytic adaptor protein.
    
 0.868
DPYD
Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.
  
 0.829
DPYS
Dihydropyrimidinase.
    
   0.809
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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