node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARID4A | ARID4B | ENSMFAP00000032226 | ENSMFAP00000025090 | AT-rich interaction domain 4A. | AT-rich interaction domain 4B. | 0.579 |
ARID4A | ENSMFAP00000010148 | ENSMFAP00000032226 | ENSMFAP00000010148 | AT-rich interaction domain 4A. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.905 |
ARID4A | HDAC2 | ENSMFAP00000032226 | ENSMFAP00000000083 | AT-rich interaction domain 4A. | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.905 |
ARID4A | KDM1A | ENSMFAP00000032226 | ENSMFAP00000000692 | AT-rich interaction domain 4A. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.706 |
ARID4A | MBD2 | ENSMFAP00000032226 | ENSMFAP00000015039 | AT-rich interaction domain 4A. | Methyl-CpG binding domain protein 2. | 0.573 |
ARID4A | MTA1 | ENSMFAP00000032226 | ENSMFAP00000016142 | AT-rich interaction domain 4A. | Metastasis associated 1. | 0.693 |
ARID4A | MTA2 | ENSMFAP00000032226 | ENSMFAP00000029081 | AT-rich interaction domain 4A. | Metastasis associated 1 family member 2. | 0.693 |
ARID4A | RB1 | ENSMFAP00000032226 | ENSMFAP00000009916 | AT-rich interaction domain 4A. | RB transcriptional corepressor 1. | 0.887 |
ARID4A | RBBP7 | ENSMFAP00000032226 | ENSMFAP00000036352 | AT-rich interaction domain 4A. | Histone-binding protein RBBP7; Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and [...] | 0.877 |
ARID4A | SIN3A | ENSMFAP00000032226 | ENSMFAP00000006874 | AT-rich interaction domain 4A. | SIN3 transcription regulator family member A. | 0.938 |
ARID4B | ARID4A | ENSMFAP00000025090 | ENSMFAP00000032226 | AT-rich interaction domain 4B. | AT-rich interaction domain 4A. | 0.579 |
ARID4B | ENSMFAP00000010148 | ENSMFAP00000025090 | ENSMFAP00000010148 | AT-rich interaction domain 4B. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.916 |
ARID4B | HDAC2 | ENSMFAP00000025090 | ENSMFAP00000000083 | AT-rich interaction domain 4B. | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.941 |
ARID4B | KDM1A | ENSMFAP00000025090 | ENSMFAP00000000692 | AT-rich interaction domain 4B. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.706 |
ARID4B | MBD2 | ENSMFAP00000025090 | ENSMFAP00000015039 | AT-rich interaction domain 4B. | Methyl-CpG binding domain protein 2. | 0.573 |
ARID4B | MTA1 | ENSMFAP00000025090 | ENSMFAP00000016142 | AT-rich interaction domain 4B. | Metastasis associated 1. | 0.726 |
ARID4B | MTA2 | ENSMFAP00000025090 | ENSMFAP00000029081 | AT-rich interaction domain 4B. | Metastasis associated 1 family member 2. | 0.704 |
ARID4B | RB1 | ENSMFAP00000025090 | ENSMFAP00000009916 | AT-rich interaction domain 4B. | RB transcriptional corepressor 1. | 0.885 |
ARID4B | RBBP7 | ENSMFAP00000025090 | ENSMFAP00000036352 | AT-rich interaction domain 4B. | Histone-binding protein RBBP7; Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and [...] | 0.884 |
ARID4B | SIN3A | ENSMFAP00000025090 | ENSMFAP00000006874 | AT-rich interaction domain 4B. | SIN3 transcription regulator family member A. | 0.945 |