Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
STK32ASerine/threonine kinase 32A; Belongs to the protein kinase superfamily. (396 aa)    
Predicted Functional Partners:
STAC2
SH3 and cysteine rich domain 2.
    
 
 0.696
A3GALT2
Alpha 1,3-galactosyltransferase 2.
    
 
 0.690
PDPK1
3-phosphoinositide dependent protein kinase 1.
    
 0.651
RPTOR
Regulatory associated protein of MTOR complex 1.
    
 0.650
MAPKAP1
MAPK associated protein 1.
    
 0.646
RICTOR
RPTOR independent companion of MTOR complex 2.
    
 0.643
CREG2
Cellular repressor of E1A stimulated genes 2; Belongs to the CREG family.
   
  
 0.638
VCAM1
Vascular cell adhesion molecule 1.
      
 0.635
TSC2
TSC complex subunit 2.
    
 0.608
APP
Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]
    
 
 0.596
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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