| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CDC42 | ENSMFAP00000012835 | ENSMFAP00000018965 | ENSMFAP00000012835 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Uncharacterized protein. | 0.900 |
| CDC42 | MPP5 | ENSMFAP00000018965 | ENSMFAP00000010415 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Membrane palmitoylated protein 5; Belongs to the MAGUK family. | 0.427 |
| CDC42 | PARD3 | ENSMFAP00000018965 | ENSMFAP00000007023 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Par-3 family cell polarity regulator. | 0.931 |
| CDC42 | PARD6A | ENSMFAP00000018965 | ENSMFAP00000015534 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Par-6 family cell polarity regulator alpha. | 0.974 |
| CDC42 | PARD6B | ENSMFAP00000018965 | ENSMFAP00000010376 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Par-6 family cell polarity regulator beta. | 0.975 |
| CDC42 | PARD6G | ENSMFAP00000018965 | ENSMFAP00000001509 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Par-6 family cell polarity regulator gamma. | 0.962 |
| CDC42 | PRKCI | ENSMFAP00000018965 | ENSMFAP00000037970 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.943 |
| CDC42 | PRKCZ | ENSMFAP00000018965 | ENSMFAP00000037413 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.946 |
| CDC42 | RAC2 | ENSMFAP00000018965 | ENSMFAP00000045826 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Rac family small GTPase 2. | 0.594 |
| CDC42 | RAC3 | ENSMFAP00000018965 | ENSMFAP00000010349 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Rac family small GTPase 3. | 0.594 |
| ENSMFAP00000012835 | CDC42 | ENSMFAP00000012835 | ENSMFAP00000018965 | Uncharacterized protein. | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | 0.900 |
| ENSMFAP00000012835 | MPP5 | ENSMFAP00000012835 | ENSMFAP00000010415 | Uncharacterized protein. | Membrane palmitoylated protein 5; Belongs to the MAGUK family. | 0.427 |
| ENSMFAP00000012835 | PARD3 | ENSMFAP00000012835 | ENSMFAP00000007023 | Uncharacterized protein. | Par-3 family cell polarity regulator. | 0.931 |
| ENSMFAP00000012835 | PARD6A | ENSMFAP00000012835 | ENSMFAP00000015534 | Uncharacterized protein. | Par-6 family cell polarity regulator alpha. | 0.974 |
| ENSMFAP00000012835 | PARD6B | ENSMFAP00000012835 | ENSMFAP00000010376 | Uncharacterized protein. | Par-6 family cell polarity regulator beta. | 0.975 |
| ENSMFAP00000012835 | PARD6G | ENSMFAP00000012835 | ENSMFAP00000001509 | Uncharacterized protein. | Par-6 family cell polarity regulator gamma. | 0.962 |
| ENSMFAP00000012835 | PRKCI | ENSMFAP00000012835 | ENSMFAP00000037970 | Uncharacterized protein. | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.943 |
| ENSMFAP00000012835 | PRKCZ | ENSMFAP00000012835 | ENSMFAP00000037413 | Uncharacterized protein. | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.946 |
| ENSMFAP00000012835 | RAC2 | ENSMFAP00000012835 | ENSMFAP00000045826 | Uncharacterized protein. | Rac family small GTPase 2. | 0.594 |
| ENSMFAP00000012835 | RAC3 | ENSMFAP00000012835 | ENSMFAP00000010349 | Uncharacterized protein. | Rac family small GTPase 3. | 0.594 |
