Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IZUMO2IZUMO family member 2. (221 aa)    
Predicted Functional Partners:
ADAM32
ADAM metallopeptidase domain 32.
      
 0.689
SPATA25
Spermatogenesis associated 25.
      
 0.689
ISOC2
Isochorismatase domain-containing protein 2; Belongs to the isochorismatase family.
      
 0.684
IZUMO3
IZUMO family member 3.
   
  
 0.668
IZUMO1
Izumo sperm-egg fusion 1.
   
  
 0.654
IZUMO4
Izumo sperm-egg fusion protein 4; Belongs to the Izumo family.
      
 0.635
RASIP1
Ras interacting protein 1.
      
 0.624
MEIOC
Meiosis specific with coiled-coil domain.
      
 0.537
SPACA6
Sperm acrosome associated 6.
      
 0.534
TMEM95
Transmembrane protein 95.
      
 0.533
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.