FTH1 protein (Macaca fascicularis) - STRING interaction network

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Your Current Organism:

Macaca fascicularis

NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CP	FECH	ENSMFAP00000026501	ENSMFAP00000011682	Ceruloplasmin; Belongs to the multicopper oxidase family.	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	0.934
CP	FTH1	ENSMFAP00000026501	ENSMFAP00000010502	Ceruloplasmin; Belongs to the multicopper oxidase family.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.907
CP	FTL	ENSMFAP00000026501	ENSMFAP00000037007	Ceruloplasmin; Belongs to the multicopper oxidase family.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.917
CP	FXN	ENSMFAP00000026501	ENSMFAP00000029296	Ceruloplasmin; Belongs to the multicopper oxidase family.	Frataxin intermediate form; Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+); the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1 (By similarity).	0.914
CP	HEPH	ENSMFAP00000026501	ENSMFAP00000042517	Ceruloplasmin; Belongs to the multicopper oxidase family.	Hephaestin; Belongs to the multicopper oxidase family.	0.903
CP	HEPHL1	ENSMFAP00000026501	ENSMFAP00000039787	Ceruloplasmin; Belongs to the multicopper oxidase family.	Hephaestin like 1; Belongs to the multicopper oxidase family.	0.902
CP	HMOX1	ENSMFAP00000026501	ENSMFAP00000044688	Ceruloplasmin; Belongs to the multicopper oxidase family.	Uncharacterized protein.	0.927
CP	HMOX2	ENSMFAP00000026501	ENSMFAP00000015152	Ceruloplasmin; Belongs to the multicopper oxidase family.	Heme oxygenase 2; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.	0.909
FECH	CP	ENSMFAP00000011682	ENSMFAP00000026501	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	Ceruloplasmin; Belongs to the multicopper oxidase family.	0.934
FECH	FTH1	ENSMFAP00000011682	ENSMFAP00000010502	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.908
FECH	FTL	ENSMFAP00000011682	ENSMFAP00000037007	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.929
FECH	FXN	ENSMFAP00000011682	ENSMFAP00000029296	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	Frataxin intermediate form; Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+); the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1 (By similarity).	0.977
FECH	HEPH	ENSMFAP00000011682	ENSMFAP00000042517	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	Hephaestin; Belongs to the multicopper oxidase family.	0.940
FECH	HEPHL1	ENSMFAP00000011682	ENSMFAP00000039787	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	Hephaestin like 1; Belongs to the multicopper oxidase family.	0.940
FECH	HMOX1	ENSMFAP00000011682	ENSMFAP00000044688	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	Uncharacterized protein.	0.936
FECH	HMOX2	ENSMFAP00000011682	ENSMFAP00000015152	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	Heme oxygenase 2; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.	0.936
FTH1	CP	ENSMFAP00000010502	ENSMFAP00000026501	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Ceruloplasmin; Belongs to the multicopper oxidase family.	0.907
FTH1	FECH	ENSMFAP00000010502	ENSMFAP00000011682	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.	0.908
FTH1	FTL	ENSMFAP00000010502	ENSMFAP00000037007	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	0.983
FTH1	FXN	ENSMFAP00000010502	ENSMFAP00000029296	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.	Frataxin intermediate form; Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+); the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1 (By similarity).	0.924

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