Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZNRF2Zinc and ring finger 2. (234 aa)    
Predicted Functional Partners:
NEURL1
Neuralized E3 ubiquitin protein ligase 1.
      
 0.657
TTLL10
Protein polyglycylase TTLL10; Polyglycylase which modifies both tubulin and non-tubulin proteins, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues of target proteins. Polyglycylates alpha-tubulin and beta-tubulin, but is not able to initiate glycylation and only has activity toward monoglycylated tubulin. Has the ability to polyglycylate non-tubulin proteins such as NAP1; in this case it can initiate glycylation and does not require preliminary monoglycylation by another glycylase (By similarity).
      
 0.535
GPATCH3
G-patch domain containing 3.
      
 0.530
PLEKHA8
Pleckstrin homology domain containing A8.
      
 0.530
RSPRY1
RING finger and SPRY domain-containing protein 1.
      
 0.516
SPATA5
Spermatogenesis associated 5.
      
 0.504
TLCD5
TLC domain containing 5.
      
 0.504
NEURL1B
Neuralized E3 ubiquitin protein ligase 1B.
      
 0.503
EAF1
ELL associated factor 1.
      
 0.500
ZNF512
Zinc finger protein 512; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
      
 0.500
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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