Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SLC18A3Solute carrier family 18 member A3. (532 aa)    
Predicted Functional Partners:
CHAT
Choline O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family.
 
 
 
 0.978
SLC17A8
Solute carrier family 17 member 8.
     
 0.960
SLC32A1
Vesicular inhibitory amino acid transporter; Involved in the uptake of GABA and glycine into the synaptic vesicles; Belongs to the amino acid/polyamine transporter 2 family.
     
 0.954
SLC17A6
Solute carrier family 17 member 6.
     
 0.950
SLC17A7
Solute carrier family 17 member 7.
     
 0.935
SLC18A1
Solute carrier family 18 member A1.
  
  
 
0.903
SLC18A2
Solute carrier family 18 member A2.
  
  
 
0.903
SYT2
Synaptotagmin 2.
     
 0.867
SYT1
Synaptotagmin-1; Calcium sensor that participates in triggering neurotransmitter release at the synapse (By similarity). May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse (By similarity). It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)- dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-in [...]
     
 0.867
VAMP2
V-SNARE coiled-coil homology domain-containing protein.
   
 
 0.845
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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