Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SMIM30Small integral membrane protein 30. (59 aa)    
Predicted Functional Partners:
NDUFB5
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
   
    0.616
GPR85
G_PROTEIN_RECEP_F1_2 domain-containing protein.
      
 0.529
ENAH
ENAH actin regulator.
      
 0.520
LOC102125097
Uncharacterized protein; Belongs to the eukaryotic ribosomal protein eL42 family.
      
 0.520
SMIM4
Small integral membrane protein 4.
      
 0.477
RPLP1
Ribosomal protein lateral stalk subunit P1; Belongs to the eukaryotic ribosomal protein P1/P2 family.
      
 0.477
ABI1
Abl interactor 1.
      
 0.440
LOC102143228
Uncharacterized protein.
   
  
 0.429
SMIM20
Uncharacterized protein.
   
  
 0.429
PFN2
Profilin-2; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
      
 0.418
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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