Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GSDMAGasdermin A. (445 aa)    
Predicted Functional Partners:
BIRC7
Baculoviral IAP repeat containing 7.
      
 0.816
DSG4
Desmoglein 4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
  
 
 
 0.792
TGM5
Transglutaminase 5.
   
  
 0.690
CASP14
Caspase 14; Belongs to the peptidase C14A family.
  
  
 0.665
CCL26
C-C motif chemokine.
      
 0.528
IL37
Interleukin-1.
      
 0.524
IL23A
Interleukin 23 p19 subunit.
  
     0.483
KRT25
Keratin 25; Belongs to the intermediate filament family.
  
 
 
 0.482
AIM2
Absent in melanoma 2.
    
 
 0.477
CASP5
Caspase 5; Belongs to the peptidase C14A family.
   
  
 0.467
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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