| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CD44 | ENSMFAP00000003734 | ENSMFAP00000024857 | ENSMFAP00000003734 | CD44 molecule (Indian blood group). | Homeobox domain-containing protein. | 0.900 |
| CD44 | ENSMFAP00000011315 | ENSMFAP00000024857 | ENSMFAP00000011315 | CD44 molecule (Indian blood group). | Homeobox domain-containing protein. | 0.935 |
| CD44 | NANOG | ENSMFAP00000024857 | ENSMFAP00000041246 | CD44 molecule (Indian blood group). | Homeobox protein NANOG; Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT] [...] | 0.900 |
| CD44 | POU5F1 | ENSMFAP00000024857 | ENSMFAP00000009913 | CD44 molecule (Indian blood group). | POU domain protein. | 0.594 |
| CD44 | STAT3 | ENSMFAP00000024857 | ENSMFAP00000002773 | CD44 molecule (Indian blood group). | Signal transducer and activator of transcription. | 0.659 |
| DDX5 | DROSHA | ENSMFAP00000013388 | ENSMFAP00000033929 | Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...] | Drosha ribonuclease III. | 0.984 |
| DDX5 | ENSMFAP00000003734 | ENSMFAP00000013388 | ENSMFAP00000003734 | Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...] | Homeobox domain-containing protein. | 0.900 |
| DDX5 | ENSMFAP00000011315 | ENSMFAP00000013388 | ENSMFAP00000011315 | Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...] | Homeobox domain-containing protein. | 0.901 |
| DDX5 | NANOG | ENSMFAP00000013388 | ENSMFAP00000041246 | Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...] | Homeobox protein NANOG; Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT] [...] | 0.900 |
| DROSHA | DDX5 | ENSMFAP00000033929 | ENSMFAP00000013388 | Drosha ribonuclease III. | Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...] | 0.984 |
| DROSHA | ENSMFAP00000003734 | ENSMFAP00000033929 | ENSMFAP00000003734 | Drosha ribonuclease III. | Homeobox domain-containing protein. | 0.900 |
| DROSHA | ENSMFAP00000011315 | ENSMFAP00000033929 | ENSMFAP00000011315 | Drosha ribonuclease III. | Homeobox domain-containing protein. | 0.905 |
| DROSHA | NANOG | ENSMFAP00000033929 | ENSMFAP00000041246 | Drosha ribonuclease III. | Homeobox protein NANOG; Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT] [...] | 0.900 |
| ENSMFAP00000003734 | CD44 | ENSMFAP00000003734 | ENSMFAP00000024857 | Homeobox domain-containing protein. | CD44 molecule (Indian blood group). | 0.900 |
| ENSMFAP00000003734 | DDX5 | ENSMFAP00000003734 | ENSMFAP00000013388 | Homeobox domain-containing protein. | Probable ATP-dependent RNA helicase DDX5; Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre- mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 t [...] | 0.900 |
| ENSMFAP00000003734 | DROSHA | ENSMFAP00000003734 | ENSMFAP00000033929 | Homeobox domain-containing protein. | Drosha ribonuclease III. | 0.900 |
| ENSMFAP00000003734 | ENSMFAP00000011315 | ENSMFAP00000003734 | ENSMFAP00000011315 | Homeobox domain-containing protein. | Homeobox domain-containing protein. | 0.915 |
| ENSMFAP00000003734 | NANOG | ENSMFAP00000003734 | ENSMFAP00000041246 | Homeobox domain-containing protein. | Homeobox protein NANOG; Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT] [...] | 0.900 |
| ENSMFAP00000003734 | STAT3 | ENSMFAP00000003734 | ENSMFAP00000002773 | Homeobox domain-containing protein. | Signal transducer and activator of transcription. | 0.900 |
| ENSMFAP00000011315 | CD44 | ENSMFAP00000011315 | ENSMFAP00000024857 | Homeobox domain-containing protein. | CD44 molecule (Indian blood group). | 0.935 |
