OR2AT4 protein (Macaca fascicularis) - STRING interaction network

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Score

OR2AT4

Olfactory receptor. (320 aa)

Predicted Functional Partners:

GNAL

0.771

GNB1

0.730

ARRB2

0.714

ARRB1

0.714

GRK2

0.699

GRK3

0.699

PRKACA

0.667

PRKACG

0.667

PRKACB

0.667

Your Current Organism:

Macaca fascicularis

NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARRB1	ARRB2	ENSMFAP00000031367	ENSMFAP00000008309	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	Arrestin beta 2.	0.962
ARRB1	GNB1	ENSMFAP00000031367	ENSMFAP00000042829	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	G protein subunit beta 1.	0.469
ARRB1	GRK2	ENSMFAP00000031367	ENSMFAP00000005645	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.944
ARRB1	GRK3	ENSMFAP00000031367	ENSMFAP00000029774	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.908
ARRB1	OR2AT4	ENSMFAP00000031367	ENSMFAP00000011444	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	Olfactory receptor.	0.714
ARRB1	PRKACA	ENSMFAP00000031367	ENSMFAP00000009922	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.473
ARRB1	PRKACB	ENSMFAP00000031367	ENSMFAP00000025214	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.469
ARRB1	PRKACG	ENSMFAP00000031367	ENSMFAP00000014434	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily.	0.473
ARRB2	ARRB1	ENSMFAP00000008309	ENSMFAP00000031367	Arrestin beta 2.	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	0.962
ARRB2	GRK2	ENSMFAP00000008309	ENSMFAP00000005645	Arrestin beta 2.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.944
ARRB2	GRK3	ENSMFAP00000008309	ENSMFAP00000029774	Arrestin beta 2.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.911
ARRB2	OR2AT4	ENSMFAP00000008309	ENSMFAP00000011444	Arrestin beta 2.	Olfactory receptor.	0.714
ARRB2	PRKACA	ENSMFAP00000008309	ENSMFAP00000009922	Arrestin beta 2.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.478
ARRB2	PRKACB	ENSMFAP00000008309	ENSMFAP00000025214	Arrestin beta 2.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.476
ARRB2	PRKACG	ENSMFAP00000008309	ENSMFAP00000014434	Arrestin beta 2.	Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily.	0.480
GNAL	GNB1	ENSMFAP00000025457	ENSMFAP00000042829	G protein subunit alpha L.	G protein subunit beta 1.	0.981
GNAL	OR2AT4	ENSMFAP00000025457	ENSMFAP00000011444	G protein subunit alpha L.	Olfactory receptor.	0.771
GNB1	ARRB1	ENSMFAP00000042829	ENSMFAP00000031367	G protein subunit beta 1.	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	0.469
GNB1	GNAL	ENSMFAP00000042829	ENSMFAP00000025457	G protein subunit beta 1.	G protein subunit alpha L.	0.981
GNB1	GRK2	ENSMFAP00000042829	ENSMFAP00000005645	G protein subunit beta 1.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.773

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