Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSMFAP00000011451Uncharacterized protein. (144 aa)    
Predicted Functional Partners:
YBX3
Y-box binding protein 3.
   
   0.938
HNRNPAB
Heterogeneous nuclear ribonucleoprotein A/B.
   
 0.874
HNRNPA2B1
Uncharacterized protein.
   
 0.851
HNRNPD
Heterogeneous nuclear ribonucleoprotein D.
   
 0.851
DHX9
DExH-box helicase 9.
   
 0.847
YBX2
Y-box binding protein 2.
   
   0.847
HNRNPU
Heterogeneous nuclear ribonucleoprotein U.
   
 0.778
TP53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]
    
 
 0.766
SYNCRIP
Uncharacterized protein.
   
 0.764
ENSMFAP00000042675
Uncharacterized protein.
   
 0.764
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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