Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
HDAC9Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1069 aa)    
Predicted Functional Partners:
NCOR1
Nuclear receptor corepressor 1.
   
 0.903
SIN3A
SIN3 transcription regulator family member A.
   
 0.852
HIST2H2BE
Histone H2B; Belongs to the histone H2B family.
    
 0.816
H2AC20
Histone H2A; Belongs to the histone H2A family.
    
 0.815
EP300
E1A binding protein p300.
    
 0.803
ARID4B
AT-rich interaction domain 4B.
    
 0.795
MEF2D
Myocyte enhancer factor 2D.
    
 
 0.793
NCOR2
Nuclear receptor corepressor 2.
   
 0.780
H2BC5
Histone H2B; Belongs to the histone H2B family.
    
 0.775
CTBP1
C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.773
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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