Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACTBL2Actin beta like 2. (376 aa)    
Predicted Functional Partners:
ACTA1
Actin alpha 1, skeletal muscle.
   
   0.974
ACTG2
Actin gamma 2, smooth muscle.
   
   0.924
ACTC1
Actin alpha cardiac muscle 1.
   
   0.855
DYNC1H1
Dynein cytoplasmic 1 heavy chain 1.
   
 0.850
ENSMFAP00000001080
Uncharacterized protein; Belongs to the actin family.
   
   0.834
ENSMFAP00000013586
Uncharacterized protein; Belongs to the actin family.
   
   0.834
ACTB
Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.
   
   0.834
ENSMFAP00000040574
Uncharacterized protein.
   
   0.834
LIMA1
LIM domain and actin binding 1.
   
 
 0.768
COL6A6
Collagen type VI alpha 6 chain.
    
 
 0.734
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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