Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
IZUMO1Izumo sperm-egg fusion 1. (350 aa)    
Predicted Functional Partners:
C4BPB
Complement component 4 binding protein beta.
      
 0.944
ZP1
Zona pellucida glycoprotein 1.
      
 0.928
IZUMO1R
IZUMO1 receptor, JUNO.
    
 
 0.905
ZP3
ZP domain-containing protein.
      
 0.742
FOLR1
Folate receptor alpha.
    
 
 0.741
SPACA1
Sperm acrosome associated 1.
   
  
 0.722
CRISP2
ShKT domain-containing protein; Belongs to the CRISP family.
   
  
 0.703
ACR
Acrosin; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome.
   
 
 0.687
CD9
Tetraspanin.
     
 0.673
SPACA6
Sperm acrosome associated 6.
    
 
 0.660
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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