Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSMFAP00000011558Uncharacterized protein. (93 aa)    
Predicted Functional Partners:
RAPGEF4
Rap guanine nucleotide exchange factor 4.
   
 0.843
APBB1IP
Amyloid beta precursor protein binding family B member 1 interacting protein.
    
 0.802
RAPGEF3
Rap guanine nucleotide exchange factor 3.
    
 0.772
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
    
 0.736
RAP1GAP
RAP1 GTPase activating protein.
    
 0.713
RAP1GAP2
RAP1 GTPase activating protein 2.
    
 0.713
RAPGEF1
Rap guanine nucleotide exchange factor 1.
    
 0.713
RAPGEF2
Rap guanine nucleotide exchange factor 2.
    
 0.709
RAPGEF6
Uncharacterized protein.
    
 0.699
ARAF
A-Raf proto-oncogene, serine/threonine kinase.
    
 0.698
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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