Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KLHL25Kelch like family member 25. (589 aa)    
Predicted Functional Partners:
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.954
ENC1
Ectodermal-neural cortex 1.
    
   0.903
PLXDC2
Plexin domain containing 2.
      
 0.824
CAND2
Cullin associated and neddylation dissociated 2 (putative).
     
 0.636
CAND1
Cullin associated and neddylation dissociated 1.
     
 0.636
USP25
Ubiquitin specific peptidase 25; Belongs to the peptidase C19 family.
    
 
 0.598
NUDCD3
NudC domain containing 3.
    
   0.589
PER3
Period circadian regulator 3.
      
 0.588
KBTBD8
Kelch repeat and BTB domain containing 8.
    
 0.587
ANAPC13
Anaphase promoting complex subunit 13.
      
 0.583
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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