DCAF15 protein (Macaca fascicularis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

DCAF15

DDB1 and CUL4 associated factor 15. (600 aa)

Predicted Functional Partners:

CHMP2A

0.650

CHMP4C

0.644

ENSMFAP00000016957

0.644

CHMP4B

0.644

IST1

0.640

CHMP6

0.635

CHMP4A

0.607

CHMP7

0.597

CHMP3

0.540

ENSMFAP00000028067

0.540

Your Current Organism:

Macaca fascicularis

NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHMP2A	CHMP3	ENSMFAP00000006522	ENSMFAP00000024393	Charged multivesicular body protein 2A.	Charged multivesicular body protein 3; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function [...]	0.977
CHMP2A	CHMP4A	ENSMFAP00000006522	ENSMFAP00000033085	Charged multivesicular body protein 2A.	Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.	0.933
CHMP2A	CHMP4B	ENSMFAP00000006522	ENSMFAP00000042579	Charged multivesicular body protein 2A.	Charged multivesicular body protein 4B.	0.949
CHMP2A	CHMP4C	ENSMFAP00000006522	ENSMFAP00000012744	Charged multivesicular body protein 2A.	Charged multivesicular body protein 4C.	0.952
CHMP2A	CHMP6	ENSMFAP00000006522	ENSMFAP00000034387	Charged multivesicular body protein 2A.	Charged multivesicular body protein 6.	0.989
CHMP2A	CHMP7	ENSMFAP00000006522	ENSMFAP00000016081	Charged multivesicular body protein 2A.	Charged multivesicular body protein 7.	0.904
CHMP2A	DCAF15	ENSMFAP00000006522	ENSMFAP00000014012	Charged multivesicular body protein 2A.	DDB1 and CUL4 associated factor 15.	0.650
CHMP2A	ENSMFAP00000016957	ENSMFAP00000006522	ENSMFAP00000016957	Charged multivesicular body protein 2A.	Uncharacterized protein.	0.924
CHMP2A	ENSMFAP00000028067	ENSMFAP00000006522	ENSMFAP00000028067	Charged multivesicular body protein 2A.	Uncharacterized protein.	0.977
CHMP2A	IST1	ENSMFAP00000006522	ENSMFAP00000029422	Charged multivesicular body protein 2A.	IST1 factor associated with ESCRT-III.	0.944
CHMP3	CHMP2A	ENSMFAP00000024393	ENSMFAP00000006522	Charged multivesicular body protein 3; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function [...]	Charged multivesicular body protein 2A.	0.977
CHMP3	CHMP4A	ENSMFAP00000024393	ENSMFAP00000033085	Charged multivesicular body protein 3; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function [...]	Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.	0.838
CHMP3	CHMP4B	ENSMFAP00000024393	ENSMFAP00000042579	Charged multivesicular body protein 3; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function [...]	Charged multivesicular body protein 4B.	0.874
CHMP3	CHMP4C	ENSMFAP00000024393	ENSMFAP00000012744	Charged multivesicular body protein 3; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function [...]	Charged multivesicular body protein 4C.	0.911
CHMP3	CHMP6	ENSMFAP00000024393	ENSMFAP00000034387	Charged multivesicular body protein 3; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function [...]	Charged multivesicular body protein 6.	0.932
CHMP3	CHMP7	ENSMFAP00000024393	ENSMFAP00000016081	Charged multivesicular body protein 3; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function [...]	Charged multivesicular body protein 7.	0.858
CHMP3	DCAF15	ENSMFAP00000024393	ENSMFAP00000014012	Charged multivesicular body protein 3; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function [...]	DDB1 and CUL4 associated factor 15.	0.540
CHMP3	ENSMFAP00000016957	ENSMFAP00000024393	ENSMFAP00000016957	Charged multivesicular body protein 3; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function [...]	Uncharacterized protein.	0.874
CHMP3	IST1	ENSMFAP00000024393	ENSMFAP00000029422	Charged multivesicular body protein 3; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function [...]	IST1 factor associated with ESCRT-III.	0.898
CHMP4A	CHMP2A	ENSMFAP00000033085	ENSMFAP00000006522	Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.	Charged multivesicular body protein 2A.	0.933

page 1 of 5

Server load: low (24%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2023

Credits

Access

Info

About