node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CENPS-CORT | GNAS | ENSMFAP00000021392 | ENSMFAP00000024110 | CENPS-CORT readthrough. | GNAS complex locus. | 0.577 |
CENPS-CORT | NPY | ENSMFAP00000021392 | ENSMFAP00000024248 | CENPS-CORT readthrough. | Neuropeptide Y. | 0.440 |
CENPS-CORT | SST | ENSMFAP00000021392 | ENSMFAP00000024737 | CENPS-CORT readthrough. | Somatostatin-14; [Somatostatin-14]: Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs ghrelin- and GnRH- stimulated secretion of GH1 and LH; the inhibition of ghrelin- stimulated secretion of GH1 can be further increased by neuronostatin. | 0.983 |
CENPS-CORT | SSTR2 | ENSMFAP00000021392 | ENSMFAP00000014106 | CENPS-CORT readthrough. | Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family. | 0.940 |
EDN1 | EDN3 | ENSMFAP00000007622 | ENSMFAP00000043694 | Endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. | Endothelin 3. | 0.960 |
EDN1 | SSTR2 | ENSMFAP00000007622 | ENSMFAP00000014106 | Endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. | Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family. | 0.722 |
EDN3 | EDN1 | ENSMFAP00000043694 | ENSMFAP00000007622 | Endothelin 3. | Endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. | 0.960 |
EDN3 | SSTR2 | ENSMFAP00000043694 | ENSMFAP00000014106 | Endothelin 3. | Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family. | 0.713 |
GHRL | NPY | ENSMFAP00000024146 | ENSMFAP00000024248 | Ghrelin and obestatin prepropeptide. | Neuropeptide Y. | 0.815 |
GHRL | SST | ENSMFAP00000024146 | ENSMFAP00000024737 | Ghrelin and obestatin prepropeptide. | Somatostatin-14; [Somatostatin-14]: Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs ghrelin- and GnRH- stimulated secretion of GH1 and LH; the inhibition of ghrelin- stimulated secretion of GH1 can be further increased by neuronostatin. | 0.720 |
GHRL | SSTR2 | ENSMFAP00000024146 | ENSMFAP00000014106 | Ghrelin and obestatin prepropeptide. | Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family. | 0.816 |
GNAI1 | GNAI2 | ENSMFAP00000008751 | ENSMFAP00000019540 | G protein subunit alpha i1. | Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). Belongs to the G-alpha family. G(i/o/t/z) subfamily. | 0.973 |
GNAI1 | GNAI3 | ENSMFAP00000008751 | ENSMFAP00000037022 | G protein subunit alpha i1. | G protein subunit alpha i3. | 0.900 |
GNAI1 | SSTR2 | ENSMFAP00000008751 | ENSMFAP00000014106 | G protein subunit alpha i1. | Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family. | 0.956 |
GNAI2 | GNAI1 | ENSMFAP00000019540 | ENSMFAP00000008751 | Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). Belongs to the G-alpha family. G(i/o/t/z) subfamily. | G protein subunit alpha i1. | 0.973 |
GNAI2 | GNAI3 | ENSMFAP00000019540 | ENSMFAP00000037022 | Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). Belongs to the G-alpha family. G(i/o/t/z) subfamily. | G protein subunit alpha i3. | 0.973 |
GNAI2 | SSTR2 | ENSMFAP00000019540 | ENSMFAP00000014106 | Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). Belongs to the G-alpha family. G(i/o/t/z) subfamily. | Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family. | 0.930 |
GNAI3 | GNAI1 | ENSMFAP00000037022 | ENSMFAP00000008751 | G protein subunit alpha i3. | G protein subunit alpha i1. | 0.900 |
GNAI3 | GNAI2 | ENSMFAP00000037022 | ENSMFAP00000019540 | G protein subunit alpha i3. | Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity). Belongs to the G-alpha family. G(i/o/t/z) subfamily. | 0.973 |
GNAI3 | SSTR2 | ENSMFAP00000037022 | ENSMFAP00000014106 | G protein subunit alpha i3. | Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family. | 0.956 |