node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMD1 | AZIN1 | ENSMFAP00000015633 | ENSMFAP00000042567 | S-adenosylmethionine decarboxylase proenzyme. | Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.770 |
AMD1 | DNMT1 | ENSMFAP00000015633 | ENSMFAP00000013116 | S-adenosylmethionine decarboxylase proenzyme. | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.902 |
AMD1 | DNMT3A | ENSMFAP00000015633 | ENSMFAP00000015995 | S-adenosylmethionine decarboxylase proenzyme. | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.900 |
AMD1 | DNMT3B | ENSMFAP00000015633 | ENSMFAP00000044977 | S-adenosylmethionine decarboxylase proenzyme. | DNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.900 |
AMD1 | MAT1A | ENSMFAP00000015633 | ENSMFAP00000038367 | S-adenosylmethionine decarboxylase proenzyme. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.934 |
AMD1 | MAT2A | ENSMFAP00000015633 | ENSMFAP00000004688 | S-adenosylmethionine decarboxylase proenzyme. | S-adenosylmethionine synthase isoform type-2; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate; Belongs to the AdoMet synthase family. | 0.934 |
AMD1 | MAT2B | ENSMFAP00000015633 | ENSMFAP00000021821 | S-adenosylmethionine decarboxylase proenzyme. | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | 0.903 |
AMD1 | SMOX | ENSMFAP00000015633 | ENSMFAP00000017161 | S-adenosylmethionine decarboxylase proenzyme. | Spermine oxidase. | 0.788 |
AMD1 | SMS | ENSMFAP00000015633 | ENSMFAP00000006256 | S-adenosylmethionine decarboxylase proenzyme. | PABS domain-containing protein. | 0.970 |
AMD1 | SRM | ENSMFAP00000015633 | ENSMFAP00000035094 | S-adenosylmethionine decarboxylase proenzyme. | PABS domain-containing protein; Belongs to the spermidine/spermine synthase family. | 0.973 |
AZIN1 | AMD1 | ENSMFAP00000042567 | ENSMFAP00000015633 | Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | S-adenosylmethionine decarboxylase proenzyme. | 0.770 |
AZIN1 | SMOX | ENSMFAP00000042567 | ENSMFAP00000017161 | Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | Spermine oxidase. | 0.760 |
AZIN1 | SMS | ENSMFAP00000042567 | ENSMFAP00000006256 | Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | PABS domain-containing protein. | 0.651 |
AZIN1 | SRM | ENSMFAP00000042567 | ENSMFAP00000035094 | Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | PABS domain-containing protein; Belongs to the spermidine/spermine synthase family. | 0.702 |
DNMT1 | AMD1 | ENSMFAP00000013116 | ENSMFAP00000015633 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | S-adenosylmethionine decarboxylase proenzyme. | 0.902 |
DNMT1 | DNMT3A | ENSMFAP00000013116 | ENSMFAP00000015995 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.994 |
DNMT1 | DNMT3B | ENSMFAP00000013116 | ENSMFAP00000044977 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | DNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.998 |
DNMT1 | MAT1A | ENSMFAP00000013116 | ENSMFAP00000038367 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. | 0.905 |
DNMT1 | MAT2A | ENSMFAP00000013116 | ENSMFAP00000004688 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | S-adenosylmethionine synthase isoform type-2; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate; Belongs to the AdoMet synthase family. | 0.905 |
DNMT1 | MAT2B | ENSMFAP00000013116 | ENSMFAP00000021821 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. | 0.918 |