STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOX3SRY-box transcription factor 3. (446 aa)    
Predicted Functional Partners:
POU5F1
POU domain protein.
    
 0.869
DMRT1
Doublesex and mab-3 related transcription factor 1.
    
 0.689
ZFX
Zinc finger protein X-linked.
   
 0.667
KLF4
Testis cDNA clone: QtsA-19426, similar to human Kruppel-like factor 4 (gut) (KLF4).
    
 0.663
ENSMFAP00000014421
Homeobox domain-containing protein.
    
 0.616
USP9X
Ubiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family.
   
 
 0.595
ZNF521
Zinc finger protein 521.
    
 0.590
RBMX
RNA-binding motif protein, X chromosome, N-terminally processed; RNA-binding protein that plays several role in the regulation of pre- and post-transcriptional processes. Implicated in tissue- specific regulation of gene transcription and alternative splicing of several pre-mRNAs. Binds to and stimulates transcription from the tumor suppressor TXNIP gene promoter; may thus be involved in tumor suppression. When associated with SAFB, binds to and stimulates transcription from the SREBF1 promoter. Associates with nascent mRNAs transcribed by RNA polymerase II. Component of the suprasplic [...]
    
 
 0.579
CTNNB1
Catenin beta 1.
    
 0.573
NR5A1
Nuclear receptor subfamily 5 group A member 1.
    
 0.572
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.