node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AP2A1 | C3orf67 | ENSMFAP00000030277 | ENSMFAP00000032837 | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] | Uncharacterized protein C3orf67 homolog. | 0.521 |
AP2A1 | DENND2C | ENSMFAP00000030277 | ENSMFAP00000021652 | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] | DENN domain containing 2C. | 0.417 |
AP2A1 | ITSN2 | ENSMFAP00000030277 | ENSMFAP00000029438 | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] | Intersectin 2. | 0.977 |
AP2A1 | RHOBTB3 | ENSMFAP00000030277 | ENSMFAP00000023998 | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] | Rho related BTB domain containing 3. | 0.405 |
C3orf67 | AP2A1 | ENSMFAP00000032837 | ENSMFAP00000030277 | Uncharacterized protein C3orf67 homolog. | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] | 0.521 |
C3orf67 | DENND2C | ENSMFAP00000032837 | ENSMFAP00000021652 | Uncharacterized protein C3orf67 homolog. | DENN domain containing 2C. | 0.581 |
CHM | DENND2C | ENSMFAP00000029908 | ENSMFAP00000021652 | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. | DENN domain containing 2C. | 0.414 |
CHM | IFT27 | ENSMFAP00000029908 | ENSMFAP00000027605 | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. | Intraflagellar transport 27. | 0.684 |
CHM | RAB35 | ENSMFAP00000029908 | ENSMFAP00000000726 | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. | RAB35, member RAS oncogene family. | 0.707 |
CHM | RAB9A | ENSMFAP00000029908 | ENSMFAP00000012307 | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. | RAB9A, member RAS oncogene family. | 0.698 |
CHM | RAB9B | ENSMFAP00000029908 | ENSMFAP00000010805 | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. | RAB9B, member RAS oncogene family. | 0.698 |
DENND2C | AP2A1 | ENSMFAP00000021652 | ENSMFAP00000030277 | DENN domain containing 2C. | AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] | 0.417 |
DENND2C | C3orf67 | ENSMFAP00000021652 | ENSMFAP00000032837 | DENN domain containing 2C. | Uncharacterized protein C3orf67 homolog. | 0.581 |
DENND2C | CHM | ENSMFAP00000021652 | ENSMFAP00000029908 | DENN domain containing 2C. | Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. | 0.414 |
DENND2C | IFT27 | ENSMFAP00000021652 | ENSMFAP00000027605 | DENN domain containing 2C. | Intraflagellar transport 27. | 0.703 |
DENND2C | ITSN2 | ENSMFAP00000021652 | ENSMFAP00000029438 | DENN domain containing 2C. | Intersectin 2. | 0.446 |
DENND2C | RAB35 | ENSMFAP00000021652 | ENSMFAP00000000726 | DENN domain containing 2C. | RAB35, member RAS oncogene family. | 0.703 |
DENND2C | RAB9A | ENSMFAP00000021652 | ENSMFAP00000012307 | DENN domain containing 2C. | RAB9A, member RAS oncogene family. | 0.550 |
DENND2C | RAB9B | ENSMFAP00000021652 | ENSMFAP00000010805 | DENN domain containing 2C. | RAB9B, member RAS oncogene family. | 0.550 |
DENND2C | RHOBTB3 | ENSMFAP00000021652 | ENSMFAP00000023998 | DENN domain containing 2C. | Rho related BTB domain containing 3. | 0.532 |