STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSSK3Testis specific serine kinase 3. (268 aa)    
Predicted Functional Partners:
PRKAB1
Protein kinase AMP-activated non-catalytic subunit beta 1.
    
 0.709
PRKAB2
Protein kinase AMP-activated non-catalytic subunit beta 2.
    
 0.709
PRKAG3
Protein kinase AMP-activated non-catalytic subunit gamma 3.
   
 0.656
PRKAG1
Uncharacterized protein.
   
 0.656
PRKAG2
Protein kinase AMP-activated non-catalytic subunit gamma 2.
   
 0.656
RPTOR
Regulatory associated protein of MTOR complex 1.
    
 0.560
MTOR
Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.
    
 0.540
SOX30
Transcription factor SOX-30; Acts as both a transcriptional activator and repressor (By similarity). Binds to the DNA sequence 5'-ACAAT-3' and shows a preference for guanine residues surrounding this core motif (By similarity). Binds to its own promoter and activates its own transcription (By similarity). Required to activate the expression of postmeiotic genes involved in spermiogenesis (By similarity). Binds to the promoter region of CTNNB1 and represses its transcription which leads to inhibition of Wnt signaling (By similarity). Also inhibits Wnt signaling by binding to the CTNNB1 [...]
     
 0.521
TP53RK
TP53 regulating kinase and related kinases.
      
 0.521
TSC2
TSC complex subunit 2.
    
 0.500
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.