STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BRIP1BRCA1 interacting protein C-terminal helicase 1. (1247 aa)    
Predicted Functional Partners:
TOPBP1
DNA topoisomerase II binding protein 1.
   
 0.998
BRCA1
Uncharacterized protein.
   
 0.998
MLH1
MutL homolog 1.
   
 0.997
BARD1
BRCA1 associated RING domain 1.
   
 0.988
BRCA2
BRCA2 DNA repair associated.
   
 0.981
PALB2
PALB2_WD40 domain-containing protein.
   
 0.977
NBN
Nibrin.
    
 0.974
WRN
WRN RecQ like helicase.
  
 0.973
PMS2
PMS1 homolog 2, mismatch repair system component.
   
 0.972
SLF1
SMC5-SMC6 complex localization factor 1.
   
 0.939
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.