STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TBC1D10ATBC1 domain family member 10A. (508 aa)    
Predicted Functional Partners:
RAB35
RAB35, member RAS oncogene family.
   
 0.828
ARF6
ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.
   
 
 0.730
SYTL1
Synaptotagmin like 1.
     
 0.698
SLC9A3R1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. Involved in sperm capacitation. May participate in the regulation of the chloride and bicarbonate homeostasis in spermatoz [...]
    
 
 0.651
IFT27
Intraflagellar transport 27.
   
 0.613
TBC1D22B
TBC1 domain family member 22B; May act as a GTPase-activating protein for Rab family protein(s).
      
 0.585
TBC1D21
TBC1 domain family member 21.
   
  
 0.547
SYTL2
Uncharacterized protein.
     
 0.534
RAB27A
RAB27A, member RAS oncogene family.
      
 0.524
TBC1D19
TBC1 domain family member 19.
      
 0.521
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.