STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEFB121Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (76 aa)    
Predicted Functional Partners:
DEFB119
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.770
DEFB113
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.745
DEFB123
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
  
  
0.740
DEFB129
Beta-defensin 129; Has antibacterial activity; Belongs to the beta-defensin family.
  
  
 0.738
SPAG11B
Uncharacterized protein.
      
 0.629
WFDC10A
WAP four-disulfide core domain 10A.
      
 0.612
GLB1L3
Beta-galactosidase.
      
 0.611
MON1B
Vacuolar fusion protein MON1 homolog B.
      
 0.611
LCN10
Lipocalin 10; Belongs to the calycin superfamily. Lipocalin family.
      
 0.610
DEFB1
Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.
  
  
 0.523
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.