node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCL20 | CCR3 | ENSMFAP00000025876 | ENSMFAP00000032252 | C-C motif chemokine. | C-C chemokine receptor type 3; Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. | 0.836 |
CCL20 | CCR5 | ENSMFAP00000025876 | ENSMFAP00000032465 | C-C motif chemokine. | C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). | 0.919 |
CCL20 | CXCL6 | ENSMFAP00000025876 | ENSMFAP00000027035 | C-C motif chemokine. | C-X-C motif chemokine. | 0.531 |
CCL20 | CXCR3 | ENSMFAP00000025876 | ENSMFAP00000016211 | C-C motif chemokine. | C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. | 0.808 |
CCL20 | CXCR4 | ENSMFAP00000025876 | ENSMFAP00000032075 | C-C motif chemokine. | C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...] | 0.903 |
CCL20 | CXCR5 | ENSMFAP00000025876 | ENSMFAP00000038993 | C-C motif chemokine. | C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. | 0.812 |
CCL20 | CXCR6 | ENSMFAP00000025876 | ENSMFAP00000045217 | C-C motif chemokine. | C-X-C chemokine receptor type 6; Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1. | 0.871 |
CCL20 | LOC102118339 | ENSMFAP00000025876 | ENSMFAP00000022303 | C-C motif chemokine. | C-X-C motif chemokine. | 0.873 |
CCL20 | LOC102124330 | ENSMFAP00000025876 | ENSMFAP00000032647 | C-C motif chemokine. | C-X-C motif chemokine. | 0.915 |
CCR3 | CCL20 | ENSMFAP00000032252 | ENSMFAP00000025876 | C-C chemokine receptor type 3; Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. | C-C motif chemokine. | 0.836 |
CCR3 | CCR5 | ENSMFAP00000032252 | ENSMFAP00000032465 | C-C chemokine receptor type 3; Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. | C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). | 0.951 |
CCR3 | CXCL6 | ENSMFAP00000032252 | ENSMFAP00000027035 | C-C chemokine receptor type 3; Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. | C-X-C motif chemokine. | 0.872 |
CCR3 | CXCR3 | ENSMFAP00000032252 | ENSMFAP00000016211 | C-C chemokine receptor type 3; Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. | C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. | 0.612 |
CCR3 | CXCR4 | ENSMFAP00000032252 | ENSMFAP00000032075 | C-C chemokine receptor type 3; Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. | C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...] | 0.763 |
CCR3 | CXCR5 | ENSMFAP00000032252 | ENSMFAP00000038993 | C-C chemokine receptor type 3; Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. | C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. | 0.475 |
CCR3 | CXCR6 | ENSMFAP00000032252 | ENSMFAP00000045217 | C-C chemokine receptor type 3; Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. | C-X-C chemokine receptor type 6; Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1. | 0.557 |
CCR3 | LOC102118339 | ENSMFAP00000032252 | ENSMFAP00000022303 | C-C chemokine receptor type 3; Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. | C-X-C motif chemokine. | 0.777 |
CCR3 | LOC102124330 | ENSMFAP00000032252 | ENSMFAP00000032647 | C-C chemokine receptor type 3; Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. | C-X-C motif chemokine. | 0.842 |
CCR5 | CCL20 | ENSMFAP00000032465 | ENSMFAP00000025876 | C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). | C-C motif chemokine. | 0.919 |
CCR5 | CCR3 | ENSMFAP00000032465 | ENSMFAP00000032252 | C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). | C-C chemokine receptor type 3; Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. | 0.951 |