node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARID4A | ARID4B | ENSMFAP00000032226 | ENSMFAP00000025090 | AT-rich interaction domain 4A. | AT-rich interaction domain 4B. | 0.579 |
ARID4A | ENSMFAP00000034298 | ENSMFAP00000032226 | ENSMFAP00000034298 | AT-rich interaction domain 4A. | Histone H3; Belongs to the histone H3 family. | 0.673 |
ARID4A | EZH2 | ENSMFAP00000032226 | ENSMFAP00000043388 | AT-rich interaction domain 4A. | Histone-lysine N-methyltransferase EZH2; Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Displays a preference for substrates with less methylation, loses activity when progressively more methyl groups are incorporated into H3K27, H3K27me0 > H3K27me1 > H3K27me2. Compared to EZH1-containing complexes, it is m [...] | 0.406 |
ARID4A | KDM2B | ENSMFAP00000032226 | ENSMFAP00000006664 | AT-rich interaction domain 4A. | Lysine demethylase 2B. | 0.418 |
ARID4A | KDM6A | ENSMFAP00000032226 | ENSMFAP00000000708 | AT-rich interaction domain 4A. | Lysine demethylase 6A. | 0.490 |
ARID4A | KDM6B | ENSMFAP00000032226 | ENSMFAP00000000852 | AT-rich interaction domain 4A. | Lysine demethylase 6B. | 0.490 |
ARID4A | LOC102121517 | ENSMFAP00000032226 | ENSMFAP00000001801 | AT-rich interaction domain 4A. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). | 0.672 |
ARID4A | SETD2 | ENSMFAP00000032226 | ENSMFAP00000003826 | AT-rich interaction domain 4A. | SET domain containing 2, histone lysine methyltransferase. | 0.593 |
ARID4B | ARID4A | ENSMFAP00000025090 | ENSMFAP00000032226 | AT-rich interaction domain 4B. | AT-rich interaction domain 4A. | 0.579 |
ARID4B | ENSMFAP00000034298 | ENSMFAP00000025090 | ENSMFAP00000034298 | AT-rich interaction domain 4B. | Histone H3; Belongs to the histone H3 family. | 0.673 |
ARID4B | EZH2 | ENSMFAP00000025090 | ENSMFAP00000043388 | AT-rich interaction domain 4B. | Histone-lysine N-methyltransferase EZH2; Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Displays a preference for substrates with less methylation, loses activity when progressively more methyl groups are incorporated into H3K27, H3K27me0 > H3K27me1 > H3K27me2. Compared to EZH1-containing complexes, it is m [...] | 0.406 |
ARID4B | KDM2B | ENSMFAP00000025090 | ENSMFAP00000006664 | AT-rich interaction domain 4B. | Lysine demethylase 2B. | 0.432 |
ARID4B | KDM6A | ENSMFAP00000025090 | ENSMFAP00000000708 | AT-rich interaction domain 4B. | Lysine demethylase 6A. | 0.490 |
ARID4B | KDM6B | ENSMFAP00000025090 | ENSMFAP00000000852 | AT-rich interaction domain 4B. | Lysine demethylase 6B. | 0.523 |
ARID4B | LOC102121517 | ENSMFAP00000025090 | ENSMFAP00000001801 | AT-rich interaction domain 4B. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). | 0.672 |
ARID4B | SETD2 | ENSMFAP00000025090 | ENSMFAP00000003826 | AT-rich interaction domain 4B. | SET domain containing 2, histone lysine methyltransferase. | 0.629 |
ENSMFAP00000034298 | ARID4A | ENSMFAP00000034298 | ENSMFAP00000032226 | Histone H3; Belongs to the histone H3 family. | AT-rich interaction domain 4A. | 0.673 |
ENSMFAP00000034298 | ARID4B | ENSMFAP00000034298 | ENSMFAP00000025090 | Histone H3; Belongs to the histone H3 family. | AT-rich interaction domain 4B. | 0.673 |
ENSMFAP00000034298 | EZH2 | ENSMFAP00000034298 | ENSMFAP00000043388 | Histone H3; Belongs to the histone H3 family. | Histone-lysine N-methyltransferase EZH2; Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Displays a preference for substrates with less methylation, loses activity when progressively more methyl groups are incorporated into H3K27, H3K27me0 > H3K27me1 > H3K27me2. Compared to EZH1-containing complexes, it is m [...] | 0.747 |
ENSMFAP00000034298 | HAT1 | ENSMFAP00000034298 | ENSMFAP00000026420 | Histone H3; Belongs to the histone H3 family. | Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. | 0.945 |