node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PSMA5 | PSMB2 | ENSMFAP00000000265 | ENSMFAP00000005305 | Proteasome subunit alpha type. | Proteasome subunit beta. | 0.999 |
PSMA5 | PSMC2 | ENSMFAP00000000265 | ENSMFAP00000030729 | Proteasome subunit alpha type. | 26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...] | 0.999 |
PSMA5 | PSMC4 | ENSMFAP00000000265 | ENSMFAP00000036504 | Proteasome subunit alpha type. | 26S proteasome regulatory subunit 6B; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated wit [...] | 0.997 |
PSMA5 | PSMC6 | ENSMFAP00000000265 | ENSMFAP00000031722 | Proteasome subunit alpha type. | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. | 0.998 |
PSMA5 | PSMD12 | ENSMFAP00000000265 | ENSMFAP00000019402 | Proteasome subunit alpha type. | PCI domain-containing protein. | 0.999 |
PSMA5 | PSMD13 | ENSMFAP00000000265 | ENSMFAP00000018426 | Proteasome subunit alpha type. | PCI domain-containing protein. | 0.998 |
PSMA5 | PSMD14 | ENSMFAP00000000265 | ENSMFAP00000005145 | Proteasome subunit alpha type. | 26S proteasome regulatory subunit N11. | 0.999 |
PSMA5 | PSMD4 | ENSMFAP00000000265 | ENSMFAP00000045865 | Proteasome subunit alpha type. | Proteasome 26S subunit, non-ATPase 4. | 0.997 |
PSMA5 | PSMD6 | ENSMFAP00000000265 | ENSMFAP00000003087 | Proteasome subunit alpha type. | Proteasome 26S subunit, non-ATPase 6. | 0.999 |
PSMA5 | USP14 | ENSMFAP00000000265 | ENSMFAP00000008344 | Proteasome subunit alpha type. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.973 |
PSMB2 | PSMA5 | ENSMFAP00000005305 | ENSMFAP00000000265 | Proteasome subunit beta. | Proteasome subunit alpha type. | 0.999 |
PSMB2 | PSMC2 | ENSMFAP00000005305 | ENSMFAP00000030729 | Proteasome subunit beta. | 26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...] | 0.995 |
PSMB2 | PSMC4 | ENSMFAP00000005305 | ENSMFAP00000036504 | Proteasome subunit beta. | 26S proteasome regulatory subunit 6B; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated wit [...] | 0.997 |
PSMB2 | PSMC6 | ENSMFAP00000005305 | ENSMFAP00000031722 | Proteasome subunit beta. | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. | 0.994 |
PSMB2 | PSMD12 | ENSMFAP00000005305 | ENSMFAP00000019402 | Proteasome subunit beta. | PCI domain-containing protein. | 0.997 |
PSMB2 | PSMD13 | ENSMFAP00000005305 | ENSMFAP00000018426 | Proteasome subunit beta. | PCI domain-containing protein. | 0.995 |
PSMB2 | PSMD14 | ENSMFAP00000005305 | ENSMFAP00000005145 | Proteasome subunit beta. | 26S proteasome regulatory subunit N11. | 0.998 |
PSMB2 | PSMD4 | ENSMFAP00000005305 | ENSMFAP00000045865 | Proteasome subunit beta. | Proteasome 26S subunit, non-ATPase 4. | 0.996 |
PSMB2 | PSMD6 | ENSMFAP00000005305 | ENSMFAP00000003087 | Proteasome subunit beta. | Proteasome 26S subunit, non-ATPase 6. | 0.995 |
PSMB2 | USP14 | ENSMFAP00000005305 | ENSMFAP00000008344 | Proteasome subunit beta. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.989 |