node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGO2 | FMR1 | ENSMFAP00000013223 | ENSMFAP00000008844 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Fragile X mental retardation 1. | 0.708 |
AGO2 | MTDH | ENSMFAP00000013223 | ENSMFAP00000044312 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Metadherin. | 0.440 |
AGO2 | SND1 | ENSMFAP00000013223 | ENSMFAP00000037792 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | 0.705 |
ERMAP | SND1 | ENSMFAP00000012571 | ENSMFAP00000037792 | Erythroblast membrane associated protein (Scianna blood group). | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | 0.623 |
FMR1 | AGO2 | ENSMFAP00000008844 | ENSMFAP00000013223 | Fragile X mental retardation 1. | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.708 |
FMR1 | SND1 | ENSMFAP00000008844 | ENSMFAP00000037792 | Fragile X mental retardation 1. | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | 0.644 |
GANAB | SND1 | ENSMFAP00000028536 | ENSMFAP00000037792 | Neutral alpha-glucosidase AB; Catalytic subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins. Required for PKD1/Polycystin-1 and PKD2/Polycystin-2 maturation and localization to the cell surface and cilia. | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | 0.719 |
MTDH | AGO2 | ENSMFAP00000044312 | ENSMFAP00000013223 | Metadherin. | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.440 |
MTDH | SND1 | ENSMFAP00000044312 | ENSMFAP00000037792 | Metadherin. | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | 0.946 |
PIWIL1 | SND1 | ENSMFAP00000030931 | ENSMFAP00000037792 | Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family. | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | 0.589 |
PIWIL1 | TDRKH | ENSMFAP00000030931 | ENSMFAP00000028829 | Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family. | Tudor domain-containing protein. | 0.709 |
PIWIL4 | SND1 | ENSMFAP00000030974 | ENSMFAP00000037792 | Piwi like RNA-mediated gene silencing 4; Belongs to the argonaute family. | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | 0.600 |
PIWIL4 | TDRKH | ENSMFAP00000030974 | ENSMFAP00000028829 | Piwi like RNA-mediated gene silencing 4; Belongs to the argonaute family. | Tudor domain-containing protein. | 0.811 |
SEC61A1 | SND1 | ENSMFAP00000024214 | ENSMFAP00000037792 | SEC61 translocon alpha 1 subunit. | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | 0.596 |
SND1 | AGO2 | ENSMFAP00000037792 | ENSMFAP00000013223 | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.705 |
SND1 | ERMAP | ENSMFAP00000037792 | ENSMFAP00000012571 | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | Erythroblast membrane associated protein (Scianna blood group). | 0.623 |
SND1 | FMR1 | ENSMFAP00000037792 | ENSMFAP00000008844 | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | Fragile X mental retardation 1. | 0.644 |
SND1 | GANAB | ENSMFAP00000037792 | ENSMFAP00000028536 | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | Neutral alpha-glucosidase AB; Catalytic subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins. Required for PKD1/Polycystin-1 and PKD2/Polycystin-2 maturation and localization to the cell surface and cilia. | 0.719 |
SND1 | MTDH | ENSMFAP00000037792 | ENSMFAP00000044312 | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | Metadherin. | 0.946 |
SND1 | PIWIL1 | ENSMFAP00000037792 | ENSMFAP00000030931 | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family. | 0.589 |