STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAD2L1BPMAD2L1 binding protein. (274 aa)    
Predicted Functional Partners:
CDC20
WD_REPEATS_REGION domain-containing protein.
   
 
 0.957
TRIP13
Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family.
   
 
 0.945
ENSMFAP00000012561
HORMA domain-containing protein.
   
 
 0.811
ENSMFAP00000013834
HORMA domain-containing protein.
   
 
 0.811
MAD2L1
Mitotic spindle assembly checkpoint protein MAD2.
   
 
 0.811
CDC20B
Cell division cycle 20B.
   
 
 0.775
FZR1
Fizzy and cell division cycle 20 related 1.
   
 
 0.586
CHST15
Carbohydrate sulfotransferase 15.
   
  
 0.534
INTU
Inturned planar cell polarity protein.
   
 
 0.532
DRAXIN
Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
      
 0.519
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.